Alzheimer's

Application: Alzheimer's disease (AD) is characterized by dementia that typically begins with memory loss a subtle and poorly recognized that worsens slowly and, over time disables the individual. Other common findings include confusion, loss of insight, language disorders, agitation, hallucinations and social withdrawal. The typical clinical duration of the disease is eight to ten years, ranging from one to 25 years. About 30% of all Alzheimer's patients are familial, of which about 95% have late onset (after 60-65 years) and 5% had early onset (before age 65).
GENE: APOE, Apolipoprotein E
Chromosomal location: 19q13.2
GENE: APP, protein precursor amyloid beta
Chromosomal location: 21q
GENE: PS1, presenilin-1 (Alzheimer disease 3)
Chromosomal location: 14q24.3
GENE: PS2, presenilin-2 (Alzheimer disease 4)
Chromosomal location: 1q

 

Alzheimer's Presinilin 1 e 2
G-1011-1

sequencing exons

4, 5, 6, 7 and intron

8 of PS1 gene

SP (EDTA) 5 ml 25 working days Sequencing
G-1011-2

sequencing exons

5, 6 and 8 gene PS2.

SP (EDTA) 5 ml 25 working days Sequencing
G-1011-3

sequencing PS1

(eg 4-7, IN8)

and PS2 (eg 5, 6 and 8).

SP (EDTA) 5 ml 25 working days Sequencing
Alzheimer
G-1012 Rev-E, PS1, 2, APP16, 17, TAU SP (EDTA) 5 ml 25 working days Sequencing
G-1012-1 Apo-E, PS1, 2, APP16, 17 SP (EDTA) 5 ml 25 working days Sequencing
G-1012-2 MAPT, CLU, PICALM, CR1 SP (EDTA) 3 ml 25 working days Sequencing

 

Patient prepare: fasting not required.
Notes: - Indicate medications used by the patient.
Storage: Refrigerated (2-8 ° C).
Stability:

07 days.

Material transportation: The material must be transported chilled (dry ice) in styrofoam boxes.
Reciving deadline: 24 hours after submission.

Note: Specify in the request correctly, the test to be performed.
Important: Fill in the form of genetic testing and Consent